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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
21.21
Human Site:
T409
Identified Species:
35.9
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
T409
G
Q
G
E
K
S
A
T
P
S
R
K
I
L
D
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
T409
G
Q
G
E
K
S
A
T
P
S
R
K
I
L
D
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
T463
G
Q
G
E
K
S
A
T
P
S
Q
K
I
L
D
Dog
Lupus familis
XP_538355
1323
142434
T409
G
Q
G
E
E
S
S
T
P
S
R
K
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
T411
G
S
G
E
E
P
A
T
P
S
R
K
I
L
D
Rat
Rattus norvegicus
NP_001012199
431
46388
E258
K
G
G
V
A
M
A
E
T
L
K
T
L
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
S411
R
S
Q
E
D
Q
K
S
T
P
K
K
I
Q
G
Chicken
Gallus gallus
NP_001006237
580
63057
E402
L
K
E
R
G
Q
G
E
Q
D
S
M
T
P
K
Frog
Xenopus laevis
O13066
580
62889
N402
E
E
G
G
D
N
E
N
K
E
K
S
K
E
I
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
E387
D
D
E
D
V
E
E
E
E
E
E
E
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
N412
E
G
D
E
E
Y
S
N
V
A
E
E
T
A
Y
Honey Bee
Apis mellifera
XP_395378
580
63771
E386
E
N
E
E
E
N
D
E
E
S
D
E
K
S
D
Nematode Worm
Caenorhab. elegans
P34342
960
105635
S568
D
L
L
E
S
P
S
S
F
S
L
E
V
L
K
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
P214
T
L
E
E
I
A
L
P
Q
N
G
I
N
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
93.3
86.6
N.A.
80
13.3
N.A.
20
0
6.6
0
N.A.
6.6
20
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
33.3
6.6
26.6
13.3
N.A.
33.3
40
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
36
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
8
8
15
0
8
0
0
8
8
0
0
0
43
% D
% Glu:
22
8
29
72
29
8
15
29
15
15
15
29
8
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
36
15
50
8
8
0
8
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
8
43
0
8
% I
% Lys:
8
8
0
0
22
0
8
0
8
0
22
43
15
0
22
% K
% Leu:
8
15
8
0
0
0
8
0
0
8
8
0
8
43
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
15
0
15
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
15
0
8
36
8
0
0
0
8
0
% P
% Gln:
0
29
8
0
0
15
0
0
15
0
8
0
0
8
8
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
29
0
0
8
0
% R
% Ser:
0
15
0
0
8
29
22
15
0
50
8
8
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
36
15
0
0
8
15
0
0
% T
% Val:
0
0
0
8
8
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _